Indicative Content
Biombrane:
Properties of membrane proteins and phospholipids.
Membrane structure models.
Energy transduction by mitochondrial and chloroplast membranes.
Membrane transport of ions and metabolites.
Organelles:
Biogenesis, function and turnover of eukaryotic cell organelles.
Nucleus: structure membranes, chromosomes and organization of DNA and RNA.
Nucleolus: sysnthesis of RNA.
Endoplasmic reticulum and Golgi apparatus. Lysosomes and peroxisomes
Learning and Teaching Strategy
The course is delivered mainly through lectures backed up by tutorial sessions and laboratory experiment.The lecture includes interactive elements whereby students in groups apply principles to simple problems to ensure their involvement and so gain understanding. Handouts are used so that students can concentrate on the material of the lecture, but with gaps where students either have to fill in or make separate notes.
Problem sheets are given out to students and after time, the problems are discussed in class. Some of the problems will be handed in and then marked by peers to give formative feedback to fellow students.
The experiment and assignment will require the students to undertake some investigation on their own and to develop ideas and apply them. They will also produce a report for each.
ASSESSMENT STRATEGY
The assessment strategy is:
- To assess knowledge and application skills though a written examination. The students therefore will not just rely on memory but also show understandings of the principles in application to exam problems.
- To assess practical skills through the report of the experiment
- To assess self learning, understanding and application through the assignment which will be ‘open ended’ so that the student has to some extent to formulate the problem and the solution.
Strategy for feedback and student support during module
·Interactive lecturing style, with opportunities for questions, and requirement to work on simple problems.
- Peer marking of tutorial questions for formative feedback.
- Marked summative assessments (laboratory report and assignment) handed back to students, with comments.
- Opportunities to consult lecturer and/or tutorial assistant in office hours.
Indicative Resources
Core Text
1. Alberts, Bruce. 2001. 4th edition. Taylor & Francis Group, 29 West 35th Street, New York, NY 10001-2299. United States of America. ISBN 0-8153-3218-1. USA.
2. Darnell J, Lodish H. And Baltimore D. 1998 Molecular Cell Biology, 2nd edition Scientific America Books, W. H. Freeman & Company, 41 Madison Avenue, New York, USA ISBN No: 0-7167-2078-9.
Background Texts
1. Lehninger A., Nelson L. D., Cox M. And Cox M. M. 2008, Principles of Biochemistry 8th edition, Freeman & Company, ISBN-10 071677108X. USA.
Journals
- Trends in Biochemistry (TIBS)
Key websites and on-line resources
https://www.ncbi.nlm.nih.gov/books/NBK21583/
Teaching/Technical Assistance
1 Lecturer,
1 Laboratory technician
Laboratory space and equipment
Bench centrifuges, UV/VIS Spectrophotometer
Computer requirements
Access to Excel (not essential)
This course of fundamental chemistry has as aim to give to all students, the essential basic theories and practicals relatives to physical chemistry, analytical chemistry and organic chemistry. These basic theories will give to the students the necessary tools for to understand, explain, apply, the studied principles to the qualitative and quantitative analysis.
This module studies also the structure of organic molecules, nomenclature, isomers and the spatial representation of organic molecules, notions of mechanisms of reactions and principal functional groups of organic compounds.
Responsible:
Sibosiko Consolee,
Ingabire Ange Sabine,
Rutikanga Adrien